Maduramicin (maduramycin) is an antiprotozoal agent used in veterinary medicine to prevent coccidiosis. It is a natural chemical compound first isolated from the actinomycete Actinomadura rubra.
Maduramicin, a polyether ionophore antibiotic derived from the bacterium Actinomadura yumaensis, is currently used as a feed additive against coccidiosis in poultry worldwide
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Use:- Maduramicin ammonium is polyether antibiotic. It’s principally used as coccidiostat for chicken. It can breach the coccidiosis by influencing electrolyte balance. It works in early developing period, 1 to 2 days after being infected. It is available to gram-positive bacteria, hyposensitive to gram-negative bacteria. Maduramycin ammonium veterinary medicine prevention and treatment because of Eimeria (Eiminriaacervulina, E. Maxima, E.mitis, E.necatrix, E.teneila) broiler coccidiosis caused.
Benefits :-
- Less toxic than other coccidiostats.
- Best compatibility with antibacterials
- Higher safety margin .Other ionophores suffer from their relatively high dosage resulting to their toxic dose being close to their therapeutic range,leading to low safety margin.
- No adverse reaction on egg production.